Ras Raf MEK ERK Signaling and the mTOR Pathway | Interactions and Regulation

The video explains the interaction between the Ras RAF MEK Erk and mtor pathways, focusing on how the Ras RAF MEK Erk pathway regulates mtor complex 1. It details the activation process of the Ras RAF MEK Erk pathway, its role in inhibiting TSC1 and TSC2, and the subsequent activation of mtor complex 1. The video also covers the downstream effects of mtor complex 1 activation, such as inhibition of autophagy and promotion of pyrimidine and protein synthesis. Additionally, it highlights the independent effects of the Ras RAF MEK Erk pathway on cell proliferation, survival, and metastasis.

What is the role of the Ras RAF MEK Erk pathway in cellular growth processes?

Describe the mechanism by which mTOR complex 1 is activated.

How does the Ras RAF MEK Erk pathway interact with the mTOR complex 1 pathway?

What is the significance of AKT in the context of the mTOR complex 1 pathway?

Explain how the Ras RAF MEK Erk pathway can lead to the activation of mTOR complex 1.

What are the downstream effects of an activated mTOR complex 1?

How does the Ras RAF MEK Erk pathway influence autophagy?