TCA / Krebs Cycle / Citric Acid Cycle - Basics for Beginners - Biochemistry Lesson

The video tutorial explains the tricarboxylic acid cycle, also known as the Krebs or Citric Acid Cycle. It covers the conversion of pyruvate to Acetyl CoA, the formation of citrate, and the subsequent steps leading to the regeneration of oxaloacetate. The tutorial highlights the regulatory mechanisms of key enzymes and the energy yield from the cycle, including ATP, NADH, and FADH2 production. It also provides mnemonic aids for remembering the sequence of reactions and discusses the energy efficiency of the cycle.

What is the primary function of the pyruvate dehydrogenase complex in the Krebs cycle?

What are the main regulatory factors affecting the activity of the pyruvate dehydrogenase complex?

What are the different substrates that can lead to the formation of Acetyl CoA?

What is the importance of oxaloacetate in the Krebs cycle?

Describe the role of citrate synthase in the Krebs cycle.

How is isocitrate converted to alpha-ketoglutarate, and what are the products of this reaction?

Discuss the process of converting succinyl-CoA to succinate and its significance.

Explain the significance of NADH and FADH2 in the Krebs cycle.

How does the Krebs cycle contribute to cellular respiration?

What is the overall yield of ATP from one complete turn of the Krebs cycle?