TCA Cycle Regulation

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Science, Chemistry, Biology
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University
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Hard
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10 questions
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1.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What is the primary role of pyruvate dehydrogenase in the TCA cycle?
To inhibit the TCA cycle
To convert acetyl CoA to pyruvate
To convert pyruvate to acetyl CoA
To synthesize ATP directly
2.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Which of the following enzymes is NOT allosteric in the TCA cycle?
Citrate synthase
Aconitase
Isocitrate dehydrogenase
Alpha-ketoglutarate dehydrogenase
3.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
High energy charge molecules like ATP and NADH generally have what effect on the TCA cycle enzymes?
They have no effect
They activate the enzymes
They convert enzymes to their inactive form
They inhibit the enzymes
4.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Which molecule is an allosteric inhibitor of citrate synthase?
ADP
Succinyl CoA
Acetyl CoA
Calcium ions
5.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What is the effect of calcium ions on isocitrate dehydrogenase?
They convert the enzyme to its inactive form
They have no effect
They activate the enzyme
They inhibit the enzyme
6.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Which enzyme in the TCA cycle is most tightly regulated?
Alpha-ketoglutarate dehydrogenase
Pyruvate dehydrogenase
Isocitrate dehydrogenase
Citrate synthase
7.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What is the role of succinyl CoA in the regulation of alpha-ketoglutarate dehydrogenase?
It converts the enzyme to its active form
It has no effect
It inhibits the enzyme
It activates the enzyme
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