Pentose Phosphate Pathway Quiz

Where does the pentose phosphate pathway occur in the cell?

• Mitochondria

• Cytosol

• Nucleus

• Endoplasmic reticulum

Which of the following is a product of the oxidative phase of the PPP?

• ATP

• NADH

• NADPH

• FADH₂

Which enzyme catalyzes the first step of the PPP?

• Hexokinase

• G6PD

• Aldolase

• Transaldolase

What is the main purpose of NADPH in cells?

• ATP production

• Oxygen transport

• Reductive biosynthesis

• DNA replication

The PPP does NOT directly produce or consume:

• CO₂

• NADPH

• ATP

• Ribose-5-phosphate

Which tissues heavily rely on NADPH for biosynthesis of fatty acids?

• Kidney and brain

• Liver and adipose tissue

• Heart and lungs

• Pancreas and spleen

What is the role of G6PD in the regulation of PPP?

• Inhibition of glycolysis

• Catalysis of reversible reactions

• Rate-limiting step

• Breakdown of ribulose

What inhibits G6PD activity?

• High NADP⁺

• Low NADPH

• High NADPH

• Insulin

Which enzyme is responsible for detoxifying hydrogen peroxide?

• Catalase

• Superoxide dismutase

• Glutathione peroxidase

• Transketolase

Which molecule is formed from ribulose-5-phosphate in the non-oxidative phase?

• Glucose

• Ribose-5-phosphate

• Pyruvate

• Glycerol