
Immunogenetics Quiz
Authored by Thathapudi Jesse Joel
Professional Development
University

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10 questions
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1.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Who introduced the concept of genetic recombination mechanisms of V, D, and J genes in the loci encoding the immunoglobulin (IG) chains?
Van Dongen JJ
Anton W. Langerak
Erasmus MC
Susumu Tonegawa
2.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What is the term used to refer to the enormous repertoire diversity of B and T lymphocytes?
Immunogenetics
Immunome
Precision Immunology
Hematology-Immunology
3.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Which technology allowed for a more high-resolution immune repertoire analysis via massively parallel sequencing?
Next-generation sequencing
Southern blot analysis
Fragment analysis
Sanger sequencing
4.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What is the spectrum of IG/TR immune repertoire diversity that can be disclosed using high-throughput sequencing technologies?
Monoclonal
Clonal
Oligoclonal
Polyclonal
5.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What phase of immune repertoire analysis involves the choice of sample type, nucleic acid type, and IG/TR targets?
Immuno-informatics phase
Analytical phase
Post-analytical phase
Pre-analytical phase
6.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Which aspect of immunogenetics allows for extraction of IG/TR repertoire sequences from -omics data sets?
Southern blot analysis
Sanger sequencing
RNA sequencing
Fragment analysis
7.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What do immunogenetic profiles constitute in the hematology-immunology domain?
Viral infections
Physiological and pathophysiological signatures of cell populations
Genetic mutations
Immune disorders
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