Citric Acid cycle & ETC

The following statements refer to the enzyme-catalyzed formation of citrate in the citric acid cycle. Which statement is false?

• Acetyl CoA is a substrate

• NADH is a product

• Coenzyme A is a product

• Oxaloacetate is a substrate

Which of the following enzymes are unique to the glyoxylate cycle

• Citrate synthase and Aconitase

• Isocitrate lyase and Malate dehydrogenase

• Isocitrate lyase and Malate synthase

• Isocitrate dehydrogenase and Malate dehydrogenase

The most important role played by the citric acid cycle in terms of total energy:

• the production of 3 NADH and 1 FADH2

• the synthesis of the “high-energy” thio-ester, succinyl-CoA

• the synthesis of ATP (or GTP) per acetyl CoA oxidized

• the oxidation of acetyl CoA to two molecules of CO2

High cellular concentrations of what molecule would inhibit the entry of pyruvate into the citric acid cycle?

• Coenzyme A

• Pyruvate

• AMP

• NADH

Which one is the mobile electron carriers?

• Coenzyme Q

• Cytochrome c oxidase

• NADH dehydrogenase

• Complex II

Where does electron transport chain happen?

• Matrix

• Cristae

• Cytoplasm

• Outer membrane

Which out of the following is termed as the active NADH shuttle?

• malate-aspartate shuttle

• glycerol-phosphate shuttle

• sodium dependent shuttle

• none of the above

ATP synthase creates ____

• energy

• adenosine diphosphate

• inorganic phosphate

• adenosine triphosphate

Which of the following statement is not true?

• most of the NADH entering the ETC arise from CA cycle

• malate-aspartate shuttle is mediated by 2 membrane carriers

• in cytosol, aspartate reverses back to oxaloacetate and lactate

• glycerol-3-phosphate through the outer mitochondrial membrane into intermembrane space

Which two organelles do we find ATP synthase?

• mitochondria and nuclei

• golgi apparatus and mitochondria

• chloroplast and nuclei

• mitochondria and chloroplast