Radiation Biological Effects

Radiation damage to DNA consists of

• DNA strand breaks

• base changes

• clustered damage

• DNA strand breaks, base changes, and

  clustered damage

Single strand break normally occur with high LET radiation.

• True

• False

A loss or change in a nitrogenous base on sugar phosphate chains may not be reversible and cause mutation.

• True

• False

Double strand break occur with high LET radiation.

• True

• False

Chromosome aberrations happen when irradiation occurs after DNA synthesis takes place.

• True

• False

In chromatid aberrations, only one chromatid of a pair suffer radiation induced-break.

• True

• False

In chromosome aberrations, both chromatid exhibit the break.

• True

• False

The effect that occurs when a tissue is irradiated with an x-ray with dose, 1000 Gy in second @ a few minutes is known as

• Instant death

• Reproductive death

• Apoptosis

• Mitotic delay

Exposing a cell to as little as 0.01 Gy of IR just before it begins cell division can cause

• Mitotic death

• Reproductive death

• Apoptosis

• Mitotic delay

Radiation may retard the mitotic process or permanently inhibit the mitotic process. This situation cause

• Mitotic delay

• Apoptosis

• Necrosis

• Mitotic death