Pretest P2 Tuesday

The best way to determine of volume of administration is based on previous research

• True

• False

Although there are references about doses from previous research, we still need to convert the dose if using different species.

• True

• False

Dose conversion model based on volume distribution and clearance values is the most used model.

• True

• False

Standard weight of human is 70 kg.

• True

• False

The volume of administration is about 30-50% from maximum volume

• True

• False

The doses that have been used in previous studies can be used as a benchmark for future research.

• True

• False

Optimization volume administration per oral for mice is 2 mL/200 g

• True

• False

Maximum volume is ..................

• maximum amount of liquid that can be accepted by an animal

• amount of liquid that can be administered to animal

• the amount of liquid that can interfere the homeostatic state of animal

• amount of liquid that consider the variability between species

• amount of liquid that result of optimization from preliminary trial

If the maximum volume of liquid given intramuscularly that can be accepted by mice is 0.05 ml, then how much volume of liquid that will be given?

• 0.05 mL

• 0.1 mL

• 0.005 mL

• 0.025 mL

• 0.5 mL

If thereis no reference from previous researches, we can use doses derived from human doses.

• True

• False