POSTLEC-BIOCHEM

Disease that is also known as Lobstein Syndrome

• Ehlers Danlos Syndrome

• Osteogenesis Imperfecta

• Knobloch Syndrome

• Chondrodysplasias

Alport syndrome is characterized by liver failure, loss of hearing and lens abnormalities.

• True

• False

Ehlers Danlos syndrome is characterized by the following EXCEPT:

• Skin Hyperextensibility

• Tissue fragility

• Hearing loss

• Articular Hypermobility

The selection, alignment and stabilization of three α chains by disulfide bonds at the carboxyl terminal happens in the:

• mitochondria

• RER

• cytoplasm

• ribosomes

It is made up of three polypeptide strands (referred to as alpha peptides) that are twisted together into a super helix or a right-handed triple helix.

• Procollagen III

• collagenase II

• procollagen

• tropocollagen

This is the type of collagen found in the basement membrane

• Type 1

• Type 2

• Type 3

• Type 4

The following are fibril forming collagens except

• III

• VI

• VII

• XI

Phase in wound repair where replacement of fibronectin-fibrin matrix occurs.

• Proliferative

• Hemostasis

• Remodeling

• Inflammatory

Macrophages become the prominent cell of this phase and where the release of various growth factors and cytokines takes place.

• Hemostasis

• Inflammatory

• Proliferative

• Remodeling

In the primary structure of fibrillar collagen, glycine is found in

• 2nd position of polypeptide chain

• 1st position of polypeptide chain

• 3rd position of polypeptide chain

• terminal position of polypeptide chain