SLS3010 neurodevelopment

Gastrulation describes the formation of which three structures?

• Endoderm, ectoderm and mesoderm

• Forebrain, midbrain and hindbrain

• Prosencephalon, mesencephalon and rhombencephalon

• Primitive streak, Hensen's node and notochord

What is released from Henson's node to initiate neural differentiation?

• BMP-2

• BMP-4

• Chordin

• Henson protein 1

What is the name of the structure indicated by the arrow?

• Neural crest

• Notochord

• Neural tube

• Epidermis

Hox gene expression is controlled by a gradient of which substance?

• NGF

• Noggin

• Chordin

• Retinoic acid

At six weeks of development, the forebrain (procencephalon) divides into which two secondary vesicles?

• Diencephalon and Mesencephalon

• Telencephalon and diencephalon

• Metencephalon and Myelencephalon

• Pontine flexure and myelencephalon

In early development all the cells of the neuroepithelium are stem cells

• True

• False

Neuronal migration occurs along which type of glial cells?

• Astrocytes

• oligodendrocytes

• Radial glial cells

• Microglia

What is A pointing to?

• Microtubules

• F-actin

• Neurofilaments

• G-actin

Apoptosis is a common feature of neural development.

• True

• False

Proneural cluster cells producing the highest amount of Delta will...

• Win the race to become neuroblasts

• Supress their neighbours' proneural genes

• Stimulate their neighbours' proneural genes

• Lose the race to become neuroblasts

• Become epidermoblasts