Important chromosomal translocations

t (11;14)

• Burkitt's lymphoma

• mantle cell lymphoma

• Hairy cell leukemia

• follicular lymphoma

t(12;22)

• Leiomyosarcoma

• Rhabdomyosarcoma

• Clear cell sarcoma

• Ewing's sarcoma

t(9;22)

• AML

• ALL

• CML

• CLL

del 1p

• Rhabdomyosarcoma

• Leiomyosarcoma

• Clear cell sarcoma

• Ewing's sarcoma

Ewing's sarcoma

• t(1,12)

• t(11;22)

• t(12;22)

• t(11,21)

Overexpression of cyclin D1 is seen in

• Burkitt's

• Mantle cell lymphoma

• Follicular lymphoma

• Hairy cell leukemia

Burkitt's lymphoma

• t(11;14)

• (8;14)

• (14;18)

• t(9;22)

Follicular lymphoma

• t(8;14)

• t(11,14)

• t(14;18)

• t(14,28)

t(x;18)

• Clear cell sarcoma

• Synovial sarcoma

• Leiomyosarcoma

• Rhabdomyosarcoma

t(2;13)

• Leiomyosarcoma

• Rhadomyosarcoma

• Clear cell sarcoma

• Synovial sarcoma