Prokaryotes vs. Eukaryotes Translation

Front

What are the elongation factors in Prokaryotes?

Back

EF-Tu (delivers tRNA), EF-G (translocation), EF-Ts (recharges EF-Tu)

Front

What are the elongation factors in Eukaryotes?

Back

eEF 1a (delivers tRNA), eEF2 (translocation), eEF1By (regenerates GTP)

Front

What are the ribosome sites in Prokaryotes?

Back

A (entry), P (peptidyl), E (exit) — same in both

Front

What are the ribosome sites in Eukaryotes?

Back

A, P, E - functionally identical

Front

How is peptide bond formation achieved in Prokaryotes?

Back

Peptidyl transferase activity from 23S rRNA in 50S subunit

Front

How is peptide bond formation achieved in Eukaryotes?

Back

Peptidyl transferase activity from 28S RNA in 60S subunit

Front

What drives translocation in Prokaryotes?

Back

EF-G-GTP drives movement of ribosome along mRNA

Front

What performs the same function as EF-G-GTP in Eukaryotes?

Back

eEF2-GTP performs the same function

Front

What are the termination factors in Prokaryotes?

Back

RF1 (UAA, UAG), RF2 (UAA, UGA), RF3 (GTPase)

Front

What are the termination factors in Eukaryotes?

Back

eRF1 (recognizes all stop codons), eRF3 (GTPase)