Coagulation | The Extrinsic Pathway of Coagulation

The video explains the intrinsic and extrinsic pathways of blood coagulation, highlighting the roles of various factors like factor 12, tissue factor, and factor 7. It details how these pathways lead to the activation of factor 10 and the conversion of prothrombin to thrombin, which then converts fibrinogen to fibrin, forming a blood clot. The video also discusses the feedback mechanisms that amplify the coagulation process, ensuring rapid clot formation to prevent blood loss.

What is the Kininogen pathway and its significance in inflammation?

Explain the difference between the intrinsic and extrinsic pathways of coagulation.

What role does tissue factor play in the extrinsic pathway?

Describe the process of how factor 7 is activated in the extrinsic pathway.

What is the significance of calcium ions in the coagulation process?

What is the function of thrombin in the coagulation process?

How does fibrinogen convert to fibrin, and why is this conversion important?

How do the intrinsic and extrinsic pathways work together in coagulation?

What challenges arise in the activation of factor 5 and thrombin?

Discuss the positive feedback mechanism in the coagulation pathways.