What Causes Runner's High?

The video explores the phenomenon of Runner's High, traditionally attributed to endorphins, which are known for pain relief but cannot cross the blood-brain barrier. Recent studies suggest endocannabinoids, similar to compounds in marijuana, might be responsible for the euphoric feelings associated with Runner's High. Research on mice and humans indicates that endocannabinoids like anandamide increase during exercise, potentially reducing pain and anxiety. However, due to small sample sizes, more research is needed to fully understand their role in humans.

What findings were reported from the 2015 study involving mice and Runners High?

What conclusions can be drawn about the involvement of endocannabinoids in Runners High based on the studies mentioned?