CLEAN : US researcher Semenza in a daze after medicine Nobel win

Greg Semenza discusses his surprise at receiving unexpected news and shares a message of encouragement to trainees, emphasizing that they will progress in their careers. He highlights the challenges in cancer treatment, particularly the lack of therapies for hypoxic cells, and the goal to develop drugs that inhibit HIF activity to improve outcomes in solid cancers.

What was Greg Semenza's initial reaction to the unexpected news he received?

• He ignored the call completely.

• He immediately celebrated.

• He thought it might be a bad joke.

• He was fully awake and expecting it.

What message does Greg Semenza convey to the trainees?

• They should focus on different research areas.

• They will never reach his level.

• They can achieve what he has achieved.

• They should change their career paths.

What is a major limitation of current chemotherapy drugs according to Greg Semenza?

• They are too expensive.

• They only target well-oxygenated dividing cells.

• They are not widely available.

• They have no side effects.

What is the focus of Greg Semenza's research in cancer therapy?

• Creating vaccines for cancer.

• Developing new surgical techniques.

• Studying the psychological effects of cancer.

• Identifying drugs to inhibit HIF activity.

Why does Greg Semenza believe targeting hypoxic cells is important?

• They do not affect the patient's health.

• They are the most visible cells.

• They survive therapy and can lead to cancer recurrence.

• They are the easiest to treat.