Cori Cycle | Lactic Acid Metabolism | Purpose and Importance in Anaerobic Metabolism

The video explains the Cori cycle, highlighting its role in converting lactate produced during anaerobic metabolism in muscles back into glucose in the liver. This process prevents lactic acidosis in muscles and ensures a continuous energy supply during intensive exercise. The cycle involves glycolysis, lactate transport, and gluconeogenesis, emphasizing the importance of maintaining energy balance and preventing muscle acidosis.

What is the primary function of the Cori Cycle?

• To increase oxygen supply to muscles

• To convert glucose into glycogen

• To produce ATP directly in muscles

• To process and remove lactic acid from muscles

During intensive exercise, what is the main source of energy for muscles?

• Glucose

• Proteins

• Amino acids

• Fatty acids

What happens to pyruvate in the absence of oxygen?

• It enters the mitochondria

• It is stored as glycogen

• It is used to produce fatty acids

• It is converted into lactate

Which enzyme is responsible for converting pyruvate to lactate?

• Aldolase

• Hexokinase

• Pyruvate kinase

• Lactate dehydrogenase

Which molecule is regenerated during the conversion of pyruvate to lactate, allowing glycolysis to continue?

• ATP

• NADH

• NAD+

• FADH2

What is the role of monocarboxylate transporters in muscle cells?

• To store glycogen

• To increase oxygen uptake

• To remove lactate and hydrogen ions from the cell

• To transport glucose into the cell

How does the liver process lactate transported from muscles?

• It converts lactate into fatty acids

• It uses lactate to produce ATP

• It stores lactate as glycogen

• It converts lactate back into glucose

What is the end product of gluconeogenesis in the liver?

• Glucose

• Pyruvate

• Lactate

• ATP

Why is the Cori Cycle considered an energy-expensive process for the liver?

• It consumes 6 ATP per glucose molecule produced

• It depletes glycogen stores

• It requires a lot of oxygen

• It produces excess lactic acid

What is the significance of the Cori Cycle during intensive exercise?

• It prevents muscle fatigue by storing glucose

• It allows continuous ATP production by recycling lactate

• It increases muscle mass

• It enhances protein synthesis