Anemia of Chronic Disease | Causes, Pathophysiology, Signs & Symptoms, Diagnosis, Treatment

The video tutorial covers anemia of chronic disease, a condition characterized by low red blood cell levels due to chronic inflammatory conditions. It discusses the pathophysiology, including the role of hepcidin in iron absorption and the impact of chronic kidney disease on erythropoietin production. Clinical features such as fatigue and weakness are highlighted, along with diagnostic methods like CBC and MCV analysis. Treatment focuses on addressing the underlying cause, with erythropoietin therapy in specific cases.

What is the primary characteristic of anemia of chronic disease?

• Low levels of hemoglobin

• Decreased inflammation

• High levels of red blood cells

• Increased iron absorption

Which hormone is primarily involved in the pathophysiology of anemia of chronic disease?

• Adrenaline

• Insulin

• Erythropoietin

• Hepcidin

How does chronic inflammation affect iron metabolism in anemia of chronic disease?

• Enhances erythropoietin synthesis

• Inhibits iron release from macrophages

• Decreases hepcidin production

• Increases iron absorption

What is the main difference in the cause of anemia in chronic kidney disease compared to anemia of chronic disease?

• Enhanced red blood cell production

• Increased iron absorption

• Decreased erythropoietin production

• Higher hemoglobin levels

Which symptom is commonly associated with anemia of chronic disease?

• Increased energy

• Fatigue

• Weight gain

• Improved concentration

What is a common diagnostic feature of anemia of chronic disease?

• Microcytic anemia

• Normocytic anemia

• Hyperchromic anemia

• Increased serum iron

Which blood test is typically used to diagnose anemia of chronic disease?

• Liver function test

• Complete blood count (CBC)

• Blood glucose test

• Lipid profile

What is the primary treatment approach for anemia of chronic disease?

• Blood transfusions

• Treating the underlying cause

• Iron supplements

• Vitamin B12 injections

In which condition is erythropoietin (EPO) therapy commonly used?

• Anemia of chronic disease

• Anemia of chronic kidney disease

• Iron deficiency anemia

• Vitamin deficiency anemia

What differentiates iron deficiency anemia from anemia of chronic disease?

• Decreased transferrin levels

• Normocytic and normochromic cells

• Microcytic and hypochromic cells

• Increased ferritin levels