The Humoral Response - B Cell Activation, Antibody Production & Memory Cells

The video explains the humoral immune response, focusing on B cell activation, antibody production, and memory cell formation. It begins with an introduction to the immune system's response to pathogens like the West Nile virus. The process of B cell activation is detailed, including antigen presentation and the role of helper T cells. The video covers clonal expansion, where B cells differentiate into plasma cells and memory B cells. Plasma cells produce antibodies that neutralize antigens, while memory B cells provide long-term immunity. The video also discusses isotype switching and affinity maturation, enhancing antibody effectiveness. The conclusion highlights the importance of the humoral response and previews the next topic on cell-mediated immunity.

What is the primary role of B cells in the immune system?

• To produce red blood cells

• To recognize and fight specific pathogens

• To transport oxygen throughout the body

• To digest food particles

What happens when a mature B cell encounters a pathogen?

• It immediately produces antibodies

• It binds to the pathogen and presents antigens

• It destroys the pathogen directly

• It becomes inactive

Which cells provide the necessary co-stimulation for B cells to become fully activated?

• Platelets

• Red blood cells

• Neurons

• Helper T cells

What is the function of plasma cells in the immune response?

• To transport nutrients

• To produce antibodies

• To break down toxins

• To store energy

How do antibodies help in fighting pathogens?

• By producing hormones

• By increasing blood pressure

• By binding to and neutralizing pathogens

• By digesting food

What is the role of memory B cells in the immune system?

• To remember specific antigens for faster response

• To digest pathogens

• To provide immediate antibody production

• To transport oxygen

What is isotype switching in the context of antibodies?

• Switching the location of immune response

• Altering the DNA sequence of B cells

• Changing the type of pathogen recognized

• Changing the class of antibody produced