Exploring Human Lifespan and Longevity

The video explores the limits of human lifespan, starting with Jeanne Calmet's record of 122 years. It discusses demographic studies showing a plateau in maximum lifespan and examines biological factors like DNA mutations and telomeres. The video also covers human longevity trials, including IGF1 and caloric restriction, and considers philosophical and evolutionary perspectives on aging. The search for extending lifespan may lead to a longer healthspan, even if immortality remains elusive.

Who holds the record for the oldest verified age in humans?

• Emma Morano

• Jiroemon Kimura

• Sarah Knauss

• Jeanne Calmet

What did the 2016 study on maximum lifespan conclude?

• The maximum lifespan has plateaued since the late 90s.

• The maximum lifespan is increasing rapidly.

• There is no limit to human lifespan.

• The maximum lifespan is decreasing.

What is one proposed biological reason for aging?

• Enhanced protein synthesis

• Increased cellular division

• Accumulation of DNA mutations

• Improved DNA repair mechanisms

What is the role of telomeres in aging?

• They prevent DNA mutations.

• They enhance DNA replication.

• They shorten over time, leading to cell division stopping.

• They increase cellular energy.

What is one challenge in conducting human longevity trials?

• Excessive funding for research

• Difficulty in finding a reliable aging marker

• Lack of interest from participants

• Too many participants

Which intervention is being tested to potentially extend lifespan in animals?

• Increased caloric intake

• IGF1 hormone manipulation

• Reduced physical activity

• Enhanced protein consumption

What is the term used to describe the proportion of life spent in good health?

• Healthspan

• Wellness period

• Vitality span

• Lifespan

What is one philosophical question raised about aging?

• Is aging a result of technological advancement?

• Is aging an evolutionary accident or programmed?

• Does aging improve cognitive abilities?

• Is aging beneficial for economic growth?

What is one potential benefit of anti-aging therapies, even if they don't extend lifespan?

• Enhanced physical strength

• Increased wealth

• Extended healthspan

• Improved memory

What is a major obstacle in determining the true cause of aging?

• Simple genetic explanations

• Complexity of molecular processes

• Lack of interest in research

• Excessive funding