Anti-diabetic Drugs in Pregnancy - MCQs

Which anti-diabetic drug is considered the first-line treatment for diabetes in pregnancy?

• Glipizide

• Metformin

• Insulin

• Pioglitazone

Which of the following oral hypoglycemic agents is MOST likely to cross the placenta?

• Insulin

• Metformin

• Acarbose

• None of the above

Which of the following anti-diabetic drugs is absolutely contraindicated in pregnancy?

• Metformin

• Insulin

• Pioglitazone

• Glibenclamide

Which of the following statements about metformin use in pregnancy is TRUE?

• It does not cross the placenta.

• It is always contraindicated in pregnancy.

• It increases insulin secretion from β-cells.

• It is sometimes used in gestational diabetes mellitus (GDM).

What is the mechanism of action of insulin in pregnancy?

• Decreases hepatic glucose production

• Stimulates insulin secretion from pancreas

• Acts as replacement for deficient endogenous insulin

• Reduces insulin resistance

In gestational diabetes, which of the following drugs is LEAST preferred?

• Insulin

• Metformin

• Glyburide (glibenclamide)

• Rosiglitazone

Why is insulin preferred over oral agents in pregnancy?

• It is more convenient to administer

• It crosses the placenta easily

• It does not cross the placenta

• It causes weight loss

Which type of insulin is most commonly used in pregnancy?

• Regular insulin and NPH

• Glargine and Detemir only

• Insulin lispro only

• Only oral hypoglycemics are used

Which of the following is a short-acting insulin safe to use in pregnancy?

• Insulin glargine

• Insulin lispro

• Insulin detemir

• Insulin degludec

A pregnant woman is on insulin therapy. What is the most common complication to watch for?

• Ketoacidosis

• Hyperkalemia

• Hypoglycemia

• Hypertension