Lecture 22 & 23– Extracellular Information

Which of the following is not a characteristic of endocrine signaling?

• Hormone acts on distant target cells

• Hormone acts on neighboring cells

• Hormone acts on the same cell that secretes it

• Hormone is secreted into the bloodstream

Which class of hormones is the largest in vertebrates?

• Steroid hormones

• Peptide hormones

• Amine hormones

• Lipid hormones

Which of the following is not a universal characteristic of signal transduction systems?

• Amplification of signal

• Irreversible binding of the ligand to the receptor

• Specificity of response

• Desensitization/adaptation

Steroid hormones typically bind to:

• Plasma membrane receptors

• G-protein coupled receptors

• Intracellular receptors

• Ion channel receptors

Which of the following is not a step in basic cell signaling?

• Reception

• Transduction

• Response

• Permanent activation of receptor

Which receptor type is most likely to bind hydrophilic messengers like insulin?

• Intracellular receptor

• Plasma membrane receptor

• Nuclear receptor

• Cytoplasmic receptor

What is a “signalosome”?

• A group of enzymes that degrade hormones

• Aggregation of receptors and ligands

• A type of hormone

• A type of receptor

Which of the following is an example of a paracrine messenger?

• Insulin

• Acetylcholine

• Cortisol

• Thyroxine

Which amino acid–derived hormones regulate smooth muscle contraction, BP, and lipolysis?

• Thyroid hormones

• Catecholamines

• Peptide hormones

• Steroid hormones

What type of receptor does cortisol bind to?

• PMR (plasma membrane receptor)

• CRP (intracellular receptor)

• G-protein coupled receptor

• Ion channel receptor