WeGoBeyond : Play to WIN Part III Quiz

Which of the following is the exclusion criteria for STEP 1 trial? (Choose all that apply)

• Age ≥ 18 years

• BMI ≥ 30

• Type 1 Diabetes

• Type 2 Diabetes

SELECT trial was conducted in diabetic population

• True

• False

Which STEP trial assessed the outcome of Semaglutide 2.4mg on sustained treatment versus withdrawal in weight-management?

• STEP 1

• STEP 2

• STEP 3

• STEP 4

The STEP 5 trial assessed the outcome of Semaglutide 2.4mg versus placebo on body weight, cardiometabolic risk factors and glucose metabolism; and safety and tolerability. What is the treatment duration for the subjects?

• 16 weeks

• 52 weeks

• 68 weeks

• 104 weeks

The STEP 10 trial assessed the effect of Semaglutide 2.4mg compared to placebo in subjects with obesity and knee osteoarthritis.

• True

• False

What is the primary outcome of SELECT Trial?

• Time to first occurrence of composite endpoint of composite HF endpoint

• Time to first occurrence of composite endpoint of 4 pt MACE

• Time to first occurrence of composite endpoint of CV death, non-fatal MI and non-fatal stroke

• weight loss from baseline

What is the trial design of SELECT Trial? (Choose all that apply)

• Multi-center

• Double-Blind

• Randomised

• Placebo-Controlled

• Event-driven superiority

In the SELECT trial, what was the relative risk reduction of the primary cardiovascular efficacy endpoint (composite of death from cardiovascular causes, non-fatal myocardial infarction, or non-fatal stroke) in Semaglutide 2.4mg versus placebo

• 20%

• 15%

• 25%

• 29%

Which of the following is not the eligible criteria used in STEP 2 trial?

• Age ≥ 18 years

• BMI ≥ 30

• Type 2 Diabetes

• Type 1 Diabetes

STEP trials with Semaglutide 2.4mg showed improvement in cardiometabolic risk factors (waist circumference, BP, HbA1C, CRP and triglycerides)

• True

• False