FINALS: WEEK 16 AND 17

Which type of influenza virus causes pandemics due to antigenic shift?

• Influenza A

• Influenza B

• Influenza C

• All types

The major surface glycoproteins of influenza virus are:

• Hemagglutinin and Neuraminidase

• Gag and Pol

• p24 and p17

• E6 and E7

Antigenic shift results from:

• Minor point mutations

• Gene segment reassortment

• Host immune pressure

• Spontaneous cell lysis

Antigenic drift leads to:

• Recombination of viral segments

• Small gradual mutations

• Sudden genome deletions

• Drug resistance

How many RNA segments does influenza A virus have?

• 6

• 8

• 10

• 12

Which protein mediates viral release in influenza virus?

• Hemagglutinin

• Neuraminidase

• Matrix protein

• Fusion protein

Which host receptor does hemagglutinin bind to?

• CD4

• MHC I

• Sialic acid

• CD8

Influenza virus replicates in which part of the host cell?

• Cytoplasm

• Mitochondria

• Nucleus

• Golgi body

Which subtype of influenza is most associated with seasonal epidemics?

• Type C

• Influenza B

• Influenza A H1N1

• All types equally

Which syndrome is associated with aspirin use in children with influenza?

• Stevens-Johnson syndrome

• Reye’s syndrome

• Kawasaki disease

• Guillain-Barré syndrome