HEMA-L3

Which of the following markers is associated with B-Lymphoid cells?

• CD41, CD61

• CD10, CD19

• CD3, CD7

Which progenitor cell gives rise to neutrophils, and what growth factor does it respond to?

• CFU-GM; GM-CSF, M-CSF, IL-3

• CFU-G; GM-CSF, G-CSF, IL-3

• CFU-MEG; Thrombopoietin, GM-CSF

Why are granulocytes more numerous than erythrocytes in a bone marrow sample?

• They are produced faster due to higher cytokine stimulation.

• They play a more critical immune function.

• They have a shorter life span of 1–2 days compared to erythrocytes’ 120-day life span.

Which cell type in granulopoiesis is characterized by a 4:1 nucleus-to-cytoplasm ratio and fine, immature chromatin?

• Promyelocyte

• Myeloblast

• Myelocyte

Which of the following features is most typical of a promyelocyte?

• Absence of granules

• Primary granules only; >20, red to burgundy

• Secondary granules predominate

What is the key cytoplasmic characteristic of a myelocyte (neutrophilic)?

• Basophilic cytoplasm with primary granules only

• Slightly basophilic to cream-colored cytoplasm with both primary and secondary granules

• Pale pink cytoplasm with rare primary granules only

Which neutrophil precursor has an indented, kidney-shaped nucleus and a 1.5:1 N:C ratio?

• Myelocyte

• Metamyelocyte

• Band neutrophil

Which stage is defined by a constricted nucleus but without threadlike filaments, and shows abundant secondary granules?

• Band (neutrophilic)

• Segmented neutrophil

• Metamyelocyte

What is the primary function of the segmented neutrophil?

• To synthesize erythropoietin

• To phagocytose pathogens using defensins and enzymes

• To transport oxygen

Which of the following is a characteristic feature of the granules found in the myelocyte (eosinophilic) stage?

• They are primarily blue-black in color.

• They are few in number and variable in color from pale orange to dark orange.

• They are absent in this stage of development.

• They are abundant and stain intensely purple.