Glycolysis Quiz

What is the primary purpose of glycolysis?

• To synthesize glucose from pyruvate

• To degrade glucose into pyruvate, producing ATP and NADH

• To convert pyruvate into lactose

• To break down proteins into amino acids

What happens to most of the energy during glycolysis?

• It is released as heat

• It is stored in the pyruvate molecules

• It is converted into NADH and released as H+ ions

• It is used to form glucose

What is the initial substrate for glycolysis?

• Pyruvate

• Oxaloacetate

• Glucose

• None of the above

According to the equation of glycolysis, what are the net products of one glucose molecule?

• 2 NADH, 2 pyruvate, 2 ATP, 2 H₂O, 4 H⁺

• 2 NAD⁺, 2 pyruvate, 2 ADP, 2 H₂O

• 2 NADH, 2 pyruvate, 4 ATP, 2 H⁺

• 2 NAD⁺, 2 pyruvate, 2 ATP, 4 H₂O

What is the main purpose of the irreversible phosphorylation of glucose by hexokinase?

• To allow glucose to diffuse out of the cell

• To trap glucose as glucose 6-phosphate inside the cell

• To break down glucose into pyruvate

• To produce ATP directly

In which step of glycolysis is the first ATP molecule produced?

• Conversion of glucose to glucose-6-phosphate by hexokinase

• Conversion of fructose-6-phosphate to fructose-1,6-bisphosphate by phosphofructokinase-1

• Conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate by phosphoglycerate kinase

• Conversion of phosphoenolpyruvate to pyruvate by pyruvate kinase

Hexokinase is one of the regulatory enzymes in glycolysis. Which of the following are also regulatory enzymes in this pathway?

• Phosphofructokinase and pyruvate kinase

• Aldolase and enolase

• Glyceraldehyde 3-phosphate dehydrogenase

• Triose phosphate isomerase

During the conversion of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate in glycolysis, what is the source of the added phosphate group?

• ATP

• GTP

• Inorganic phosphate (Pi)

• FAD

How does glucose-6-phosphate (Glu-6P) affect hexokinase and glucokinase?

• It inhibits both enzymes

• It inhibits hexokinase but not glucokinase

• It inhibits glucokinase but not hexokinase

• It activates both enzymes

What is the name of the enzyme that catalyzes the irreversible phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate in glycolysis?

• Hexokinase

• Glucokinase

• Phosphofructokinase (PFK-1)

• Pyruvate kinase