AP Biology DNA Practice Test
Authored by Tess Bernhard
Biology, Science
11th - 12th Grade
NGSS covered
Used 390+ times
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About
This AP Biology DNA Practice Test comprehensively covers the molecular basis of heredity at the 11th-12th grade level, focusing on DNA structure, replication, transcription, translation, and cell division. Students must demonstrate mastery of complex biochemical processes including the semi-conservative model of DNA replication, the directional synthesis of leading and lagging strands, and the role of specific enzymes like DNA polymerase, primase, and ligase. The quiz requires deep understanding of Chargaff's rules, base pairing principles, and the structural components of nucleotides. Advanced topics include RNA processing in eukaryotes (5' capping, 3' poly-A tailing, and splicing), genetic code degeneracy, mutation effects, gene regulation through promoter sequences, and the central dogma of molecular biology. Students must also understand mitotic cell cycle phases, chromosome behavior during division, and cell cycle regulation through cyclins and CDKs. Created by Tess Bernhard, a Biology teacher in US who teaches grade 11-12. This assessment serves multiple instructional purposes, functioning effectively as a comprehensive review tool before AP Biology exams, formative assessment to gauge student understanding of molecular genetics, or homework assignment to reinforce classroom instruction on DNA and cell division. The quiz can be strategically deployed as a warm-up activity to activate prior knowledge before introducing related topics, or as targeted practice for students preparing for standardized assessments. This material directly supports AP Biology Learning Objectives 3.1-3.6 and 3.28, covering DNA replication mechanisms, gene expression regulation, and cell cycle control. The assessment aligns with NGSS standards HS-LS1-4 (modeling DNA to RNA to protein information flow) and HS-LS3-1 (asking questions to clarify gene expression relationships), providing teachers with valuable data on student mastery of these essential molecular biology concepts.
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31 questions
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1.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
How do the leading, and the lagging strands differ?
2.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Suppose a double-stranded DNA molecule was shown to have 15% adenine bases. What would be the expected percentage of guanine bases in that molecule?
3.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Consider the replication bubble diagrammed at the right. Which letters represent leading strands?
4.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Which enyzme would be found only on the lagging strand?
5.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Which enzyme is not working correctly if new DNA bases are not added to the template strand?
6.
MULTIPLE CHOICE QUESTION
2 mins • 1 pt
What is meant that DNA replication follows a “semi-conservative” model?
7.
MULTIPLE CHOICE QUESTION
1 min • 12 pts
Which RNA bases would pair with TACGAA in transcription?
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