Chromosomal Mutations and Genetic Disorders

What type of gene mutation has occurred here?

Normal: AGA-TTC-ATA-GCG

Mutant: AGA-TTC-AAT-AGC-G

• Base deletion

• Base insertion

• Base substitution

• Base inversion

Name the mutation that happens when an extra base has been added to the sequence of bases.

• Base substitution

• Base deletion

• Base inversion

• Base insertion

Tags

NGSS.HS-LS3-2

__________ occurs when the DNA change does not alter the amino acid sequence of the polypeptide.

• Frameshift mutation

• Base insertion

• Missense mutation

• Silent mutation

DNA molecule segment is : TTACGCAAG

The mutated DNA segment is TTACGCAAC. This is an example of _______ mutation.

• Base substitution

• Base insertion

• Base inversion

• Translocation

Tags

NGSS.HS-LS3-2

What's the gender and disorder?

• Male - Down Syndrome

• Female - Down Syndrome

• Male - Turner Syndrome

• Female - Turner Syndrome

Tags

NGSS.HS-LS3-1

NGSS.HS-LS3-2

Identify the mutation in the picture.

• Deletion

• Inversion

• Duplication

• Translocation

Tags

NGSS.HS-LS3-2

Which of the following are types of euploidy? (answer can be more than ONE)

• Polyploidy

• Aneuploidy

• Allopolyploidy

• Autopolyploidy

The failure of one or more pairs of homologous chromosomes or sister chromatids to separate "normally" during meiosis is called _____________________.

• nondisjunction

• duplication

• deletion

• translocation

Tags

NGSS.HS-LS3-2

Nondisjunction

• When a segment of a chromosome breaks off.

• When a segment of a chromosome breaks off, flips, and reattaches.

• When a segment of a chromosome breaks and attaches to a non homologous chromosome.

• When entire chromosomes don't separate evenly during meiosis.

• When a segment of a chromosome is copied or doubles.

This Karyotytpe belongs to which syndrome?

• Turner Syndrome

• Edwards Syndrome

• Patau Syndrome

• Down Syndrome

• Klinefelter Syndrome

Tags

NGSS.HS-LS3-1