Foreign Body Response

What cells are considered the detectives?

• macrophages

• neutrophils

• lymphocytes

• fibroblasts

• neurons

What is the main difference between acute and chronic inflammation?

• Acute inflammation involves a rapid response while chronic involves a sustained response with tissue damage

• Acute inflammation leads to scar tissue formation while chronic does not

• Acute inflammation involves only lymphocytes, while chronic involves only macrophages

• Acute inflammation involves a long-term response while chronic is short-term

• Acute inflammation is more fun than chronic

What role do macrophages play when they are activated?

• 1. They start forming fibrotic tissue.

• They begin to clean up and digest the foreign material.

• They recognize past intruders and prepare a future response.

• They recruit lymphocytes to start inflammation response.

• Destroy the microphages.

How does changing the shape of the protein affect the body's response?

• It makes the proteins more recognizable to the immune cells.

• 1. It helps macrophages to phagocytosis pathogens.

• It repairs the damage and builds new tissue.

• It may develop into chronic inflammation with tissue damage.

• It makes you skinny.

What is the first thing that happens when a foreign object enters the body?

• They say hi to the immune cells.

• The immune system starts generating lymphocytes right away.

• The body forms scar tissue around the foreign body.

• The foreign body is immediately removed by immune cells.

• The foreign body interacts with body fluid and blood plasma proteins.

What is the purpose of forming a fibrous tissue around the foreign body?

• Getting it dressed for the occasion.

• To reduce the visibility of the foreign body to the immune cells.

• To immediately remove it.

• To isolate and contain the foreign body.

• To enhance the immune response.

What role do fibroblasts play in the later stages of inflammation?

• They build new tissue and repair damage.

• They immediately attack and destroy the foreign body.

• They detect previous intruders and prepare a future response.

• They suppress the immune response to reduce inflammation.

• They get the party started.

What is the role of neutrophils?

• They form fibrotic tissue

• They are the first responders and neutralize the problem quickly.

• They clean up and repair damaged

• They remember past intruders

• They have no role, they are neutral.

What concept is related to the response to foreign bodies and biomedical application?

• Mindfulness

• Work hardening

• Elasticity

• Biomechanics

• Biocompatibility

What triggers the transition from acute inflammation to chronic inflammation?

• A switch in the foreign body.

• The characteristics of the foreign body.

• The absence of immune cells at the site of inflammation.

• The persistence of the foreign body and ongoing damage tissue.

• The immediate removal of the foreign body.