Telmisartan Quiz

Telmisartan is used to treat which of the following conditions?

• Diabetes

• High Blood Pressure

• Asthma

• Hypothyroidism

Telmisartan does not appear to be metabolized by:

• CYTOCHROME-P450

• Liver enzymes

• Kidney enzymes

• Intestinal enzymes

Telmisartan can cross which of the following barriers in the body?

• Blood-brain barrier

• Placental barrier

• Skin barrier

• Intestinal barrier

Telmisartan is metabolized in the liver to:

• Glucuronide acid

• Hydrochloride salt

• Sulfate conjugate

• Phosphate ester

What is the primary mode of action of Telmisartan?

• Inhibits renin release

• Blocks the attachment of Angiotensin II to ATI Receptor

• Increases heart rate

• Reduces blood volume

Which of the following statements is true about the absorption of Telmisartan?

• Tmax is 2-4 hours

• Bioavailability is 42-58%

• It has low lipophilicity

• It is metabolized by CYTOCHROME-P450

Telmisartan's plasma protein binding capacity is:

• 70%

• 80%

• 90%

• > 99.5%

Which of the following is not an indication for the use of Telmisartan?

• Hypertension

• Cardiovascular protection

• Improved insulin sensitivity

• Use in pregnant women

Which of the following is a contraindication for Telmisartan use?

• Hypertension

• Heart Failure

• Paediatrics

• Improved insulin sensitivity