Heterochromatin/Cancer/Dynein

What is the structure of a nucleosome?

• A nucleosome consists of RNA wrapped around a core of histone proteins.

• A nucleosome consists of DNA wrapped around a core of non-histone proteins.

• A nucleosome consists of DNA wrapped around a core of histone proteins.

• A nucleosome consists of RNA wrapped around a core of non-histone proteins.

What is the role of histones in chromatin structure?

• Histones are responsible for DNA replication.

• Histones are involved in RNA transcription.

• Histones protect DNA from damage.

• Histones organize and compact DNA into a condensed form.

What is the difference between heterochromatin and euchromatin?

• Heterochromatin is loosely packed and transcriptionally active, while euchromatin is tightly packed and transcriptionally inactive.

• Heterochromatin and euchromatin have the same level of packing and transcriptional activity.

• Heterochromatin and euchromatin are both transcriptionally inactive.

• Heterochromatin is tightly packed and transcriptionally inactive, while euchromatin is loosely packed and transcriptionally active.

Transcriptionally active chromatin is called

• Euchromatin

• Heterochromatin

• Chromatonema

The histone proteins present in a histone octamer are

• H2A,H2B,H2C,H3

• H2A,H2B,H1,H3

• H2A,H2B,H3,H4

The chromatin which stains dark and tightly packed

• Euchromatin

• Chromatophore

• Heterochromatin

Wrapping of negatively charged DNA around positively charged histone octamer is called

• Nucleosome

• Chromatin

• Chromosome

• Histone

What can cancer cells do that normal cells cannot?

• they do everything the same

• they regenerate their telomeres, preventing them from aging

• they go through cellular division

• they grow

What gene is often mutated to become inactive which can lead to cancers?

• p57

• EVR 1

• p53

• telomerase

What are the motor protein(s) of microtubules?

• Actin

• Myosin

• Kinesin/Dynein

• N/A