Neurodegenerative Disease

Condition that causes the demyelination of the CNS

Type of MS that has one exacerbation with full recovery (rare)

• Relapsing Remitting

• Primary progressive

• Progressive relapsing

• Benign

Types of MS that has regular exacerbations with significant recovery after each.

• Benign

• Primary remitting

• Relapsing remitting

• Progressive relapsing

Type of MS that has regular exacerbation with little to no recovery after each.

• Primary progressive

• Benign

• Progressive relapsing

• Relapsing remitting

Type of MS that has no recovery after regular exacerbations (rare).

• Benign

• Progressive relapsing

• Primary progressive

• Relapsing remitting

Four cardinal signs:

1. 1. resting tremor

2. 2. Rigidity

3. 3. Bradykinesia

4. 4. Postural instability

PD: Unilateral symptoms, typically a resting tremor, with no or minimal loss of function

• Stage 3

• Stage 5

• Stage 1

• Stage 4

PD: Bilateral symptoms; balance is not affected, although problems develop with trunk mobility and postural reflexes

• Stage 1

• Stage 3

• Stage 5

• Stage 2

_{PD: Impaired balance secondary to postural instability resulting in mild to moderate impairments in function}

• Stage 4

• Stage 1

• Stage 5

• Stage 3

PD: Decrease in postural stability, decrease in function, impaired mobility, need for assistance with ADLs, poor fine motor and dexterity.

• Stage 4

• Stage 1

• Stage 5

• Stage 3