Antiseizure Medications (ASMs)

Sodium Valproate Extended-Release Tablet is available as:

• 200mg/tablet

• 400mg/tablet

• 500mg/tablet

There are 2 strength of phenytoin capsule available in our hospital, which are 30 mg and 300 mg per capsule.

• True

• False

What is the target range of Phenytoin?

• 5-10 mg/L

• 10-20 mg/L

• 20-40 mg/L

TDM Phenytoin Level is 14.2 mg/L but serum creatinine is unavailable.
What is your interpretation?

• Below therapeutic range

• Within therapeutic range

• Incomplete Data for Interpretation

Maximum loading dose of IV Phenytoin for an adult is 2000 mg or 30 mg/kg.

• True

• False

TDM Levetiracetam is available in our hospital.

• True

• False

Carbamazepine Tablet is available as CR 200 mg, CR 400 mg and IR 200 mg per tablet in our hospital formulary.

• True

• False

Due to autoinduction, initial dose of carbamazepine can be given up to the maximum dose.

• True

• False

Patient is on IV Phenytoin 100 mg TDS and phenytoin pre level is 17 mg/L. If patient is still fitting, can suggest to increase to IV Phenytoin 100/100/130mg TDS.

• True

• False

Patient with hypoalbuminemia will have lower phenytoin level than the measured TDM level.

• True

• False