Voltage-Sensitive Calcium Channels (VSCCs) Quiz

What is the role of the fourth transmembrane segment in VSCCs?

• Regulates calcium entry

• Acts as a voltmeter

• Forms the pore

• Regulates neurotransmitter release

Which amino acids serve as an ionic filter for calcium ions in VSCCs?

• Connecting segments 6 and 1

• Connecting segments 5 and 6

• Connecting segments 3 and 4

• Connecting segments 1 and 2

How many subunits come together to form the pore of VSCCs?

• Three

• Five

• Two

• Four

What is the role of the α2δ protein in VSCCs?

• Regulates blood pressure

• Acts as a pore inactivator

• Is targeted by anticonvulsants

• Regulates neurotransmitter release

Which subtype of VSCCs is found in the central nervous system and affects blood pressure?

• P/Q channels

• R channels

• L channels

• N channels

What is the presynaptic role of N and P/Q VSCCs?

• Regulate blood pressure

• Regulate neurotransmitter release

• Regulate electrical impulses

• Regulate synaptic vesicles

How do anticonvulsants interact with VSCCs?

• Regulate blood pressure

• Prevent excessive neurotransmission

• Trigger synaptic vesicles

• Modulate electrical impulses

What is the process of conversion of an electrical impulse into a chemical message triggered by calcium entry through VSCCs called?

• Synaptic transmission

• Neurotransmitter modulation

• Excitation–Secretion Coupling

• Voltage regulation

What is the main clinical application of anticonvulsants in relation to VSCCs?

• Treating bipolar disorders

• Treating chronic pain

• Treating migraines

• All of the above

What is the significance of understanding VSCCs in psychopharmacology?

• Treating psychiatric conditions

• Modulating neurotransmitter release

• All of the above

• Regulating blood pressure