LE#4.1 Glycoysis

What is the first step of glycolysis that involves the addition of a phosphate group to glucose?

• Decarboxylation

• Phosphorylation

• Oxidation

• Dehydration

Which enzyme is responsible for the phosphorylation of glucose to glucose-6-phosphate?

• amylase

• pepsin

• lipase

• hexokinase

What is the energy investment in terms of ATP required for the phosphorylation of glucose?

• 10 molecules of ATP

• 5 molecules of ATP

• 2 molecules of ATP

• 1 molecule of ATP

Explain the role of hexokinase in the process of glucose phosphorylation.

• Hexokinase phosphorylates glucose to form glucose-6-phosphate.

• Hexokinase converts glucose to fructose

• Hexokinase breaks down glucose into pyruvate

• Hexokinase converts glucose to glycogen

During glycolysis, how many molecules of ATP are produced through substrate-level phosphorylation?

• 6

• 2

• 8

• 4

Which enzyme catalyzes the conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate in glycolysis?

• pyruvate kinase

• phosphoglycerate kinase

• fructose-1,6-bisphosphatase

• glucose-6-phosphatase

What is the net gain of ATP molecules from glycolysis per molecule of glucose?

• 10 ATP molecules

• 0 ATP molecules

• 2 ATP molecules

• 5 ATP molecules

Describe the role of phosphoglycerate kinase in the production of ATP during glycolysis.

• It catalyzes the conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate, generating ATP.

• It is not involved in the production of ATP during glycolysis

• It converts glucose to pyruvate without generating ATP

• It inhibits the production of ATP during glycolysis

In glycolysis, which molecule is reduced to produce NADH?

• Glucose-6-phosphate

• Glyceraldehyde-3-phosphate

• Pyruvate

• ATP

What is the role of glyceraldehyde-3-phosphate dehydrogenase in NADH generation during glycolysis?

• It has no role in NADH generation

• It converts NADH to glyceraldehyde-3-phosphate

• It inhibits the generation of NADH

• It catalyzes the conversion of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate, generating NADH.