Gupta Kahoot

Which of the following GLP-1 agonists has the longest half life?

• Semaglutide (Ozempic)

• Dulaglutide (Trulicity)

• Liraglutide (Victoza)

• Exenatide (Byetta)

Which of the following causes a fruity scent (like nail polish remover) type smell in patients with diabetic ketoacidosis?

• Acetoacetic acid

• Plasma bicarbonate

• Beta-hydroxybutyric acid

• Acetone

Increased glucose leads to PARP activation, which in turn inactivates Protein Kinase C

• True

• False

Which of the following GLUT receptor types promotes glucose uptake in fat cells?

• 4

• 3

• 2

• 1

Different insulin formulations have different efficacy as well as pharmacokinetics

• True

• False

All of the following amino acids residues in insulin can be modified except

• AsnA21

• ProB28

• ThrB30

• GylB23

Which of the following is NOT a complication of diabetes

• Hypoglycemia

• Slow healing of feet wounds

• Peripheral neuropathy

• Cognitive impairment

Which of the following is NOT secreted by pancreatic cells?

• GLP-1

• Amylin

• Insulin

• Glucagon

Which of the following is INACTIVATED by insulin

• Glycogen synthesis

• Growth promoting genes

• Lipase

• Protein synthesis

Pioglitazone works by inhibiting

• PPAR-y

• DPP-4

• alpha-Glucosidase

• SUR