BIO EXAM Partial Questions

What type of genetic regulation seems to be the most similar between prokaryotes and eukaryotes?

• 5'-capping regulation

• Poly-A tail addition

• Transcriptional regulation

• RNA splicing regulation

We can find repressors in _________

• Prokaryotes

• Eukaryotes

• Both

A regulatory sequence of DNA (that is 10,000 base pairs away from the gene it regulates) is mutated. The result is that the gene being regulated is now expressed at a higher rate compared to when this regulatory sequence was not mutated. What would this sequence of DNA best be called?

• Core promoter

• Enhancer

• Silencer

• Activator

• Proximal promoter element

Is a silencer cis or trans?

• Cis

• Trans

True or False. An enhancer can be found downstream to a promoter.

• True

• False

How would you define TFIID?

• General transcription factor

• Specific transcription factor

Put each option in the right category.

Groups:

(a) General transcription factor

,

(b) Specific transcription factor

• Essential for basal transcription

• Binds to the promoter

• Binds to the enhancers

The prokaryotic counterpart of the general transcription factors is __________.

Protein X is made at a high level in one cell type and a low level in another cell type. Why?

• The two cell type have different sets of cis elements: (enhancers/silencers)

• The two cell types have a different set of transcription factors (activators/repressors)

• Both of the choices

If we look at the same gene in different cell types, we will see the (same or different) ________ DNA - including the promoter and all its regulatory elements.