DNA Polymerase Quiz

What is the main enzymatic activity of DNA polymerase?

• Catalyzing the formation of phosphodiester bonds

• Repairing DNA damage

• Facilitating DNA replication

• Breaking phosphodiester bonds

Which subunit of DNA polymerase is responsible for the proofreading function?

• Ligase domain

• 3' to 5' exonuclease domain

• 5' to 3' exonuclease domain

• Polymerase domain

What is the function of the proofreading activity of DNA polymerase?

• To increase the speed of DNA replication.

• To break down DNA molecules.

• To prevent DNA replication from occurring.

• To detect and correct errors in DNA replication.

What is processivity in the context of DNA polymerase?

• Ability to catalyze the addition of multiple nucleotides by dissociating from the template DNA

• Ability to catalyze the addition of a single nucleotide without dissociating from the template DNA

• Ability to catalyze the addition of multiple nucleotides without dissociating from the template DNA

• Ability to catalyze the addition of nucleotides in the reverse direction

Which domain of DNA polymerase is responsible for its processivity?

What is the role of the exonuclease activity in DNA polymerase?

• The exonuclease activity in DNA polymerase is responsible for breaking down proteins.

• The exonuclease activity in DNA polymerase is responsible for proofreading and repairing errors in DNA replication.

• The exonuclease activity in DNA polymerase is responsible for initiating DNA replication.

• The exonuclease activity in DNA polymerase is responsible for transcribing RNA.

Which DNA polymerase has the highest processivity?

• DNA polymerase I

• DNA polymerase III

• DNA polymerase II

• DNA polymerase IV

What is the role of the sliding clamp in DNA replication?

• The sliding clamp helps to unwind the DNA during replication.

• The sliding clamp acts as a proofreading enzyme during replication.

• The sliding clamp is responsible for repairing damaged DNA during replication.

• The sliding clamp helps to hold the DNA polymerase onto the DNA strand during replication.

Which DNA polymerase is responsible for the synthesis of the leading strand during DNA replication?

• DNA polymerase III

• DNA polymerase IV

• DNA polymerase I

• DNA polymerase II

What happens if the proofreading function of DNA polymerase is impaired?

• Decrease in errors or mutations in the DNA strand

• Increase in errors or mutations in the DNA strand

• Increase in the speed of DNA replication

• No effect on errors or mutations in the DNA strand