Immunology Formative Assessment

Complement component C3 is cleaved by

• C3b

• C3bBb

• Factor B

• Factor D

The membrane attack complex consists of

• OH

• Colicins

• C3b3b,Bb

• C5b,6,7,8,9

Which of the following is not an acute phase protein?

• Serum amyloid P component

• Chondroitin sulphate

• C-reactive protein

• Mannose binding lectin

A complement component strongly chemotactic for neutrophils is

• C9

• C3

• C5a

• C3b

Specific antibodies are readily detectable in serum following with primary contact with antigen after

• 10 min

• 1 h

• 3–5 weeks

• 5–7 days

Intracellular parasites within macrophages are killed more readily in the presence of

• Antibody

• Kinins

• Properdin

• Gamma-interferon

The basic IgG unit is composed of:

• 2 identical heavy and 2 different light chains

• 2 identical heavy and 2 identical light chains

• 2 different heavy and 2 different light chains

• Non covalently bound polypeptides

IgA is seromucus secretions

• A Has no J-chain

• Has no secretory piece

• Is dimeric

• Cannot bind to neutrophils

Affinity is the measure of strength of the binding of antigen to antibody

• True

• False

Superantigens bind to MHC Class III

• True

• False