PHO231 lec 8

The nicotinic receptor is a type of

• Ligand gated ion channel

• G protein-coupled receptor

• Receptor coupled to kinase activity

• Modulation of DNA transcription

The beta 1 receptor is coupled to Gs protein which leads to

• Stimulation of adenylate cyclase

• Inhibition of adenylate cyclase

• Stimulation of phospholipase C

• Stimulation of IP3

The thyroid hormone receptor is an example of

• Ligand gated ion channel coupled receptor

• G protein coupled receptor

• Intracellular receptor

• Tyrosine kinase linked receptor

Atropine is a muscarinic blocker and is an example of

• Competitive blocker

• Non competitive blocker

This blocker causes non-parallel shift of dose response curve to right and decreased efficacy

• Competitive blocker

• Non-competitive blocker

Long use of salbutamol a beta 2 agonist causes

• Up regulation of the receptor

• Down regulation of the receptor