Chapter 9

Which type of genomics deals with the identification of the complete sequence of a genome and gene map?

• a) Structural genomics

• b) Functional genomics

• c) Comparative genomics

What is the focus of functional genomics?

• a) The identification of complete genome sequences

• b) The functioning of genes and their regulation

• c) Comparison of genes from different genomes

Comparative genomics is the study of:

• a) The functioning of genes and their regulation

• b) The identification of complete genome sequences

• c) Comparison of genes from different genomes

How is the proportion of repetitive DNA calculated?

• a) Genome size multiplied by length of repetitive DNA e

• b) Genome size divided by length of repetitive DNA

• c) Length of repetitive DNA divided by genome size

What are the two categories of repetitive DNA?

• a) Tandem repeats and transposons

• b) Interspersed repeats and satellites

• c) Retrotransposons and micro-satellites

What is a tandem repeat?

• a) A sequence of DNA bases that is repeated numerous times in a head-to-tail manner on a chromosome

• b) A highly repetitive non-coding DNA consisting of short sequences repeated a large number of times

• c) A copy of transposition element inserted at other places in the genome

What is satellite DNA?

• a) A sequence of DNA bases that is repeated numerous times in a head-to-tail manner on a chromosome

• b) A highly repetitive non-coding DNA consisting of short sequences repeated a large number of times

• c) A copy of transposition element inserted at other places in the genome

Which category of repetitive DNA makes up one third of DNA repeats?

• a) Tandem repeats

• b) Interspersed repeats

• c) Transposable elements

What is the most relevant type of tandem repeat or satellite DNA to medicine?

• a) Macrosatellites

• b) Minisatellites

• c) Microsatellites

Which type of repetitive DNA comprises about 15% of the human genome?

• a) LINES

• b) SINES

• c) Tandem repeats