Pediatric CPB

The vast majority of oxygenators for Cardiopulmonary bypass are

• Microporous

• Hollow fiber

• True Membrane

• Bubble

• Synthetic

Filter housing are usually clear to facilitate________

Which of the following is not a complication associated with clot in bypass circuit?

• Inability of the bypass oxygenator to function properly

• Malfunctioning pump

• Patient embolic event

•    Stroke

•      Neurological dysfunction

Anticoagulation is required to prevent activation of

• coagulation pathway

• Intrinsic pathway

• Extrinsic pathway

• Common pathway

• Blood exposed to non-endothelial surfaces

At what minimum age the antithrombin III levels approach normal adult values?

• Puberty

• Six months

• 24 months

• One Year

• 28 days

Which of the following is protamine titration dosing?

• Data points of baseline heparin and after heparin bolus

• Higher protamine dosing for additional heparin on bypass

•   1 mg protamine for 100 units of heparin estimation

•    Exposing varying amounts of heparin and protamine doses

• Neutralize heparin effect by 1:1 ratio of protamine

Accidental administration of protamine on bypass

• Underreported

•   Frequently occurring

•    Rare complication

•      Lethal complication

•     Unusual

Alpha stat

•     Ionized beta imidazole of histadine

•     Maintains intracellular ph

•    Maintains cellular blood flow autoregulation

• normoxic

• hyperoxic

Oxygen molecule binds to the hemoglobin molecule tightly leads to

•   Optimum tissue absorption

•   Poor tissue level absorption

•    Vasoconstriction

•     Right shift of oxyhemoglobin dissociation curve

• Microvasculature blockage

Maintaining the natural balance of (H+) ions relative to hydroxide ions with the imidazole of histidine and other systems is important in maintaining______