WK-4 Live Test

Choose the correct one seen in nuclear end of the NPC.

• Ran.GDP

• Importin

• Ran. GTP

• Exportin.Ran.GDP

CRM1 is necessary for the export of mRNA.

• True

• False

Since the first nucleotides cannot be linked in a newly synthesized strand in DNA replication( in vivo ), ___________ is required.

• a DNA primer

• DNA polymerase

• ligase

• an RNA primer

Which statement about the elongation of the lagging strand during DNA replication is correct?

• It is synthesized in a 3' --> 5' direction

• It progresses (grows) toward the replication fork

• It requires a short RNA primer to proceed.

• It is synthesized by DNA ligase.

DNA replication is called semiconservative because _______________ of the original duplex appears in the duplex formed in replication.

• none

• most

• half

• hardly any

A 4-year-old child, on a well-child checkup, is found to have a large flank mass. Computed tomography demonstrates a large mass arising from the kidney, and a subsequent biopsy reveals a diagnosis of Wilms tumor. A pediatric oncologist starts chemotherapy including the transcription inhibitor actinomycin D. Which of the following statements is correct regarding transcription regulation in bacteria?

• All mRNAs are monocistronic.

• RNA polymerase requires a primer

• Rho factor is critical for initiation of RNA synthesis

• The TATA box contains a consensus sequence for the binding of RNA polymerase

RNA polymerase dismounts after transcription of first 150 nucleotides in Trp operon. This is termed as

• anti-termination

• attenuation

• catabolite repression

A hydrophillic ligand binds to a(n) ______________, when a chemical messenger (or ligand) reaches target cell.

• intracellular receptors

• transımembrane receptors

• intercellular receptors

• autocrine receptors

_____________ receptors activate signalling pathways usually by forming molecular dimers that result in protein phosphorylation reactions upon binding of their specific ligand.

• Steroid hormone

• Receptor tyrosine kinase

• Ligand gated ion channel

• G protein coupled

_____________ enzyme does not require a primer.

• RNA dependent DNA polymerase

• DNA dependent DNA polymerase

• DNA dependent RNA polymerase