GI Immunology Quiz

What cells (directly) present antigens to T cells and lymph nodes?

• Peyer's Patches

• M cells

• Dendritic Cells

• Epithelial Cells of GI

Where do T and B cells interact with antigens to get activated?

• Primary Lymphoid Organs (Bone Marrow, Thymus)

• Secondary Lymphoid Organs (Lymph nodes, spleen)

• Liver

• Kidneys

Which T cell type is unique to ulcerative colitis?

• Th2

• Th1

• Treg

• Th17

When a naive T cell enters a lymph node, which molecules must it use? Or which receptor must it use?

Where in a lymph node do B cells proliferate, undergo hypermutation, and class switch recombination?

• Germinal centre(s)

• Paracortex

• Cortex

• Medulla

An 8 year old boy comes in complaining of itchy and red eyes, along with a runny and congested nose after playing outside in the park on a summer day. What type of hypersensitivity reaction is most likely being displayed?

• I

• II

• III

• IV

A patient has come in complaining of recurrent stomach pain. They are having diarrhoea (no blood) + fever, and are feeling quite fatigued. They haven't been experiencing any weight loss. Which of the following diseases best fits this profile?

• Crohn's Disease

• Ulcerative Colitis

• Coeliac's Disease

• Colon cancer

Which antibody type is found the most in the gut?

• IgA

• IgE

• IgG

• IgM

• IgD

Treg cells, which are a subset of CD4+ T helper cells, express which of the following transcription factors?

• FoxP3

• CCR9

• a4b7

• MadCAM

Which ILs are associated with Th2?