Pharmacology Mock Exam 1

An order is written for two highly protein bound drugs. What is your major concern?

• Bone loss

• Hyperlipemia

• Toxicity

• Malabsorption

A nurse understands that a decrease in villi caused by a disease or removal of intestines will affect which pharmacokinetic process:

• Distribution

• Absorption

• Metabolism

• Excretion

The nurse understands that administration of lidocaine was not ordered by oral route and therefore will not be subjected to

• toxicity

• first pass effect

• absorption

• liver damage

You know the nursing student understands the concept of IV drugs in relation to bioavailability, if he says:

• The bioavailability is 75%

• Oral drugs are relatively more bioavailable than IV drugs

• Bioavailability of IV drugs is 100%

• IV drugs are non-bioavailable

What is the priority nursing intervention when administering digoxin, a medication with a narrow therapeutic index?

• Assessment for fall risks

• Checking of vital signs

• Monitoring plasma drug levels

• Monitoring respiratory rates

The student nurse is aware that the following affect drug bioavailability. Select all that apply.

• Drug form

• Gastric motility

• Route of administration

• Changes in liver function

• Right patient

Sulbactam intensifies the action of ampicillin and this causes stronger therapeutic effects. You understand this interaction as

• Synergism

• Additive effects

• Antagonism

• Maximal efficacy

The nurse is caring a cancer patient who has been on pain medications for several weeks. The patient complains that their pain medication is no longer helping like it used to. The nurse's best response would be:

• "It's possible you developed a tolerance to the drug. Let's ask the healthcare provider about changing your dose or medication."

• "It's possible your cancer has gotten worse and you're no longer going to respond to the pain medication."

• "Unfortunately we worry that you will become addicted to these meds, and we won't be able do much else."

• "Have you tried deep breathing exercises to get through the pain?"

True or False?

Peak levels are drawn before the next dose of drug is administered.

• True

• False

True or False?

A diseased kidney majorly affects drug metabolism.

• True

• False