Atherosclerotic Cardiovascular Disease (ASCVD) Overview

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Atherosclerotic Cardiovascular Disease (ASCVD)

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Often called CVD for short.

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Risk Factors, Pathophysiology & Treatment

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Key areas of study for Atherosclerotic Cardiovascular Disease (ASCVD).

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ASCVD

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ASCVD stands for Atherosclerotic Cardiovascular Disease, characterized by the narrowing of blood vessels and decreased elasticity.

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Progressive growth of plaques

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Atheromas are the progressive growth of plaques in the arteries.

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Endothelial injury leads to

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Endothelial injury leads to inflammation.

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Contributors to ASCVD

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Foam cells, platelets, and fibrin contribute to ASCVD.

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Effect of narrowing arteries

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Narrowing of arteries results in decreased blood flow.

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Factors causing endothelial injury

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Hypertension, smoking, diabetes, and LDL can cause endothelial injury.

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Rupture of plaques

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When plaques rupture, they can break off, form a thrombus, and cause further endothelial injury.

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Pathophysiology: Scarring & thickening of vessel wall

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Scarring and thickening of the vessel wall can lead to less flexible and reactive vessels.