Immune System Response

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Immune System Response Diagram

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Foreign antigen invades, causing an antigenic response.

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Antiretroviral therapy goal

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To be undetected and untransmissible by keeping CD4 cells high and viral load low.

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Adherence issue in antiretroviral therapy

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Taking multiple doses a day is a problem for adherence.

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Health disparities in HIV treatment

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Affects mostly men from minority backgrounds with a 40% decrease in CD4 cells.

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CD4 cell count below 200

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Diagnosed with AIDS, often with one opportunistic infection, and wasting (10% decrease in ideal body weight).

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Most common opportunistic infections in AIDS

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Kaposi's Sarcoma (KS) and Pneumocystis pneumonia.

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Treatment focus for AIDS patients

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Treat their current problems as they can have many complications.

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Graph showing the relationship between HIV viral load, CD4+ T cells, and HIV-specific antibody blood levels over time.

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IgG

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The most abundant type of antibody, found in all body fluids, protects against bacterial and viral infections.

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IgA

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Found in high concentrations in mucous membranes, particularly in the respiratory passages and gastrointestinal tract, as well as in saliva and tears.