Classification of Parenterals

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Small Volume Parenteral (SVP)

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Volume is less than 100 mL and generally used as vehicles for medications.

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Administration of Drug Solutions

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Both small and large volumes of drug solutions may be administered intravenously.

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Primary use of small-volume parenterals includes therapeutic injections like insulin.

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Size range of large-volume parenteral products.

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100 mL to 1000 mL; larger sizes (e.g., 3000 mL) can be used for parenteral nutrition products.

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Large Volume Parenterals (LVP) are sterile.

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Many LVP are sterilized in their container via heat, although some are sterile-filled.

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LVP contain no anti-microbial agents.

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These solutions do not include anti-microbial agents to prevent contamination.

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LVP administration method.

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Administered by slow IV with or without a controlled-rate infusion system.

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Parenteral incompatibilities

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Be aware of parenteral incompatibilities, e.g., calcium and phosphate when admixed in PN bags.