Psychopharmacology Basics

Front

The average resting membrane potential (RMP) is

Back

-70 to -75 mV

Front

What mainly occurs during DEPOLARIZATION in the neuron?

Back

Na ions rapidly enter the cell

Front

What is true regarding the Na- K ATPase pump?

Back

Pumps 3 Na outside and 2 K inside

Front

The correct sequence of release of Neurotransmitters from the vesicles is: Release, Dock, Merge; Merge, Dock, Release; Dock, Merge, Release; Dock, Release, Merge

Back

Dock, Merge, Release

Front

Serotonin is to 5 HT 2 A what _____ is to Receptor

Back

Ligand

Front

A ligand is also known as a _____ messenger.

Back

First

Front

Dopamine and most serotonin receptors are of which type?

Back

G-protein coupled receptors

Front

Ion channel receptors may be opened by which means?

Back

Either of the two depending upon type of receptor

Front

What happens at the D2 R when Haloperidol acts? Options: Receptor activity maximizes, Receptor comes to baseline (constituent) activity, Receptor functions at sub-maximal (but greater than baseline) activity , All (including baseline) activity stops at the receptor

Back

Receptor comes to baseline (constituent) activity

Front

Which of the following is most likely to produce rapid relief in symptoms? Drugs acting on nuclear receptors (eg oestrogen), Drugs acting on ion channel receptors (eg lorazepam- BDZ), Drugs acting on receptors associated with tyrosine kinase (RTK) (eg Imatinib for cancers), Drugs acting on G-protein coupled receptors (eg Olanzepine- antipsychotic)

Back

Drugs acting on ion channel receptors (eg lorazepam- BDZ)