DNA and Genetic Research

Front

genetic blueprint containing all genetic information necessary for protein production and gene expression.

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DNA

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DNA stands for

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2-deoxyribonucleic acid

Front

Who isolated nuclein (now known as DNA) from the nucleus of WBCs in 1860s?

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Friedrich Miescher

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What did Friedrich Miescher do in 1860s?

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isolated nuclein (now known as DNA) from the nucleus of WBCs

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Who observed the transforming principle in mice in 1928?

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Frederick Griffith

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What did Frederick Griffith observe in 1928?

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The transforming principle in mice.

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What were the 4 conditions and results of Griffith's Experiment?

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1. Rough strains (nonvirulent) - mouse lives.

2. Smooth strains (virulent) - mouse dies.

3. Heat-killed smooth strains - mouse lives.

4. Rough strains + heat-killed smooth strains - mouse dies.

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What conclusion did Griffith's Experiment lead to?

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Some type of molecule was transferred from dead bacteria to live bacteria, transforming them into the smooth strain.

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Who discovered DNA as the transforming principle?

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Oswald Avery, Colin Macleod, Maclyn McCarty.

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What did Oswald Avery, Colin Macleod, and Maclyn McCarty discover?

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DNA as the transforming principle