Which of the following is a key substance required for the incorporation of vitamin B12 in the nuclear synthesis of red blood cells? EPO, Transferrin, Intrinsic factor, Homocysteine
Macrocytic anemia

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1.
FLASHCARD QUESTION
Front
Back
Intrinsic factor
2.
FLASHCARD QUESTION
Front
Evidence of a megaloblastic anemia includes: Microcytic RBCs, Thrombocytosis, Decreased red cell precursors with other cell lines unaffected, Pancytopenia
Back
Pancytopenia
3.
FLASHCARD QUESTION
Front
All of the following are possible causes of low levels of intrinsic factor (IF) except: Gastrectomy, Pernicious anemia, Gastritis, Kidney failure
Back
Kidney failure
4.
FLASHCARD QUESTION
Front
Which MCV range is indicative of pernicious anemia? Options: 70 -80, 85 - 95, 95-105, 110-120
Back
110-120
5.
FLASHCARD QUESTION
Front
Which of the following RBC morphologies is classic in the megaloblastic anemias? Polychromasia, Macro ovalocytes, Macrocytes, Hypochromia
Back
Macro ovalocytes
6.
FLASHCARD QUESTION
Front
Intrinsic factor is secreted by the:
Back
Parietal cells
7.
FLASHCARD QUESTION
Front
The Schilling test continues to be a historic reference method for the determination of: IDA, Pernicious anemia, Folic acid deficiency, Non megaloblastic anemia
Back
Pernicious anemia
8.
FLASHCARD QUESTION
Front
Macrocytic RBCs are routinely seen in all of the following except: Pernicious anemia, Liver disease, Response to anemic stress, Thalassemia
Back
Thalassemia
9.
FLASHCARD QUESTION
Front
Which of the following is a clinical symptom specific to B12 deficiency? Fever, Numbness and trouble with balance, Pallor, Splenomegaly
Back
Numbness and trouble with balance
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